Our long-term research goal is to understand gene regulation in the context of a 3D genome. Using the bipotential gonad as a model, we aim to decipher how cellular fate is determined and maintained in vivo and how this information is encoded in the mammalian genome (learn more here).

Our methodology combines different approaches to detect regulatory elements and state-of the-art technologies to define and perturb regulatory landscapes in vivo to assess their functionality (learn more here).